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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1990-4-16
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pubmed:abstractText |
Mitochondrial myopathies can affect the skeletal muscle, the central or peripheral nervous system, and they may be associated with chronic progressive external ophthalmoplegia (CPEO). In 7/29 patients with mitochondrial myopathies and CPEO a cardiac involvement (Kearns-Sayre syndrome) was found: incomplete right bundle branch block (n = 1), right bundle branch block (n = 1), left anterior fascicular block and right bundle branch block (n = 2), complete atrioventricular block (n = 3); congestive cardiac failure (ejection fraction 40%) (n = 2); 3/10 patients had prolonged infranodal conduction on His-bundle electrography (HV-interval 60 ms). The cardiac involvement in ophthalmoplegia plus is characterized by progressive impairment of fascicular conduction. The need for prophylactic pacemaker implantation appears to exist in patients with bifascicular block and prolonged His-ventricle conduction.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0300-5860
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
60-5
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:2316277-Adolescent,
pubmed-meshheading:2316277-Adult,
pubmed-meshheading:2316277-Bundle-Branch Block,
pubmed-meshheading:2316277-Electrocardiography, Ambulatory,
pubmed-meshheading:2316277-Female,
pubmed-meshheading:2316277-Heart Block,
pubmed-meshheading:2316277-Heart Conduction System,
pubmed-meshheading:2316277-Humans,
pubmed-meshheading:2316277-Kearns-Sayre Syndrome,
pubmed-meshheading:2316277-Male,
pubmed-meshheading:2316277-Middle Aged,
pubmed-meshheading:2316277-Ophthalmoplegia,
pubmed-meshheading:2316277-Pacemaker, Artificial
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pubmed:year |
1990
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pubmed:articleTitle |
[Indications for pacemaker therapy in ophthalmoplegia plus and Kearns-Sayre syndrome].
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pubmed:affiliation |
Medizinische Universitätsklinik, Univ.-Nervenklinik, Bonn.
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pubmed:publicationType |
Journal Article,
English Abstract
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