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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1990-4-26
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pubmed:abstractText |
In 1986, a prospective cohort study on diet and cancer was started in The Netherlands. The cohort (n = 120, 852) of 55-69 year old men (48.2%) and women (51.8%) originates from 204 computerized municipal population registries. At baseline, participants completed a self-administered questionnaire on diet and potential confounding variables. In addition, about 67% of the participants provided toenail clippings. Cancer follow-up consists of record linkage to a pathology registry and to cancer registries. The initial interest is in stomach, colorectal, breast and lung tumors. A case-cohort approach is applied, in which detailed follow-up information of a random subcohort (n = 5000) provides an estimate of the person-time experience of the cohort. Exposure data of the subcohort will be combined with those of incident cases, yielding exposure-specific incidence rate ratios. The intraindividual variation in determinants is estimated by annually repeated measurements (n = 250) within the subcohort. The rationale, efficiency aspects and study characteristics are discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0895-4356
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
285-95
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2313318-Aged,
pubmed-meshheading:2313318-Cohort Studies,
pubmed-meshheading:2313318-Diet,
pubmed-meshheading:2313318-Female,
pubmed-meshheading:2313318-Humans,
pubmed-meshheading:2313318-Male,
pubmed-meshheading:2313318-Middle Aged,
pubmed-meshheading:2313318-Neoplasms,
pubmed-meshheading:2313318-Netherlands,
pubmed-meshheading:2313318-Prospective Studies,
pubmed-meshheading:2313318-Questionnaires,
pubmed-meshheading:2313318-Registries,
pubmed-meshheading:2313318-Risk Factors,
pubmed-meshheading:2313318-Smoking
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pubmed:year |
1990
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pubmed:articleTitle |
A large-scale prospective cohort study on diet and cancer in The Netherlands.
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pubmed:affiliation |
Department of Epidemiology, University of Limburg, Maastricht, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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