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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1980-4-17
|
| pubmed:abstractText |
Arginine supplements were given to 6 week old CBA mice beginning 3 days prior to inoculation with a murine sarcoma virus, the Moloney Sarcoma Virus (MSV). Although the basal diet contained 1.8% arginine and was therefore not arginine-deficient, supplementation of the diet and the drinking water with 0.5% arginine HCl reduced tumor incidence, lengthened the latency period, decreased tumor size, and hastened tumor regression. Arginine also increased thymic weight and cellularity in normal and in MSV-inoculated mice. The antitumor action of arginine may be related to its effect on the thymus.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0148-6071
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
3
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
409-16
|
| pubmed:dateRevised |
2007-2-21
|
| pubmed:meshHeading |
pubmed-meshheading:231121-Adrenal Glands,
pubmed-meshheading:231121-Animals,
pubmed-meshheading:231121-Arginine,
pubmed-meshheading:231121-Body Weight,
pubmed-meshheading:231121-Lymphocytes,
pubmed-meshheading:231121-Male,
pubmed-meshheading:231121-Mice,
pubmed-meshheading:231121-Mice, Inbred CBA,
pubmed-meshheading:231121-Organ Size,
pubmed-meshheading:231121-Sarcoma, Experimental,
pubmed-meshheading:231121-Sarcoma Viruses, Murine,
pubmed-meshheading:231121-Thymus Gland
|
| pubmed:articleTitle |
Supplemental arginine increases thymic cellularity in normal and murine sarcoma virus-inoculated mice and increases the resistance to murine sarcoma virus tumor.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
|