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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1990-4-6
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pubmed:abstractText |
Open lung biopsies from 14 patients and autopsy tissue from one patient with polymyositis/dermatomyositis were reviewed in an attempt to correlate histologic features with clinical, radiographic, and prognostic variables. Three major groups based on histologic patterns were identified: bronchiolitis obliterans organizing pneumonia (BOOP), usual interstitial pneumonia (UIP), and diffuse alveolar damage (DAD). Patients with BOOP had a more favorable prognosis than did patients with UIP. Patients with DAD had a uniformly poor prognosis. One patient had a cellular interstitial pneumonia and did well. Histologic subclassification of the interstitial lung disease proved to be a better predictor of survival than did the radiographic appearance or the clinical presentation. These findings suggest that there is a broader range of histologic findings in polymyositis-dermatomyositis than is suggested in the literature and subclassification may be useful for prognosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0003-0805
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
141
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
727-33
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2310101-Adult,
pubmed-meshheading:2310101-Aged,
pubmed-meshheading:2310101-Biopsy,
pubmed-meshheading:2310101-Bronchiolitis Obliterans,
pubmed-meshheading:2310101-Dermatomyositis,
pubmed-meshheading:2310101-Female,
pubmed-meshheading:2310101-Humans,
pubmed-meshheading:2310101-Lung,
pubmed-meshheading:2310101-Male,
pubmed-meshheading:2310101-Middle Aged,
pubmed-meshheading:2310101-Myositis,
pubmed-meshheading:2310101-Pneumonia,
pubmed-meshheading:2310101-Prognosis,
pubmed-meshheading:2310101-Pulmonary Alveoli,
pubmed-meshheading:2310101-Pulmonary Fibrosis,
pubmed-meshheading:2310101-Retrospective Studies
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pubmed:year |
1990
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pubmed:articleTitle |
Interstitial lung disease in polymyositis and dermatomyositis. Clinical features and prognosis as correlated with histologic findings.
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pubmed:affiliation |
Department of Pathology, Mayo Clinic, Rochester, MN 55905.
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pubmed:publicationType |
Journal Article
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