Linked Life Data

2309677

Source:http://linkedlifedata.com/resource/pubmed/id/2309677

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-4-3
pubmed:abstractText
Little is known about the uptake of small particles by the epithelium of the gastrointestinal tract. In our study, we investigated the absorption and transport of synthetic and natural particles by means of scanning electron microscopy (SEM). In Wistar rats, closed loops of jejunum with intact mesenteric blood supply were established in ether anesthesia so that we might study the absorption of latex particles of different sizes. After variable absorption times, loops were removed and prepared for examination by microscopic techniques. The average surface of M-cells was 35 +/- 2 microns2, whereas the total number was dependent on follicle size. The proportion of M-cells to absorptive-like enterocytes on follicle epithelium was 1:12. Latex particles were found easily on the surface of M-cells, and for the most part they were surrounded by microfolds. In only 10 min from the time of application, latex beads were concentrated or even included within macrophages of the dome of lymph follicles. The results indicate that primary insorption of small particles occurs in M-cells of Peyer's patches, and time of insorption is dependent on particle size.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0002-9270
pubmed:author
pubmed:issnType
Print
pubmed:volume
85
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
255-60
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Rapid insorption of small particles in the gut.
pubmed:affiliation
Department of General Surgery, Christian-Albrechts-University Kiel, West Germany.
pubmed:publicationType
Journal Article