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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1990-4-10
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pubmed:abstractText |
The role of anthropometric variables in the risk of breast cancer has been investigated using pooled data from 2 hospital-based case-control studies conducted in Italy for a total data-set of 3,247 cases and 3,263 controls. No association was observed in pre-menopausal women between breast cancer risk and height, weight, indices of body mass (W/H2; W/H1.5) and surface area. In post-menopausal women, the risk of breast cancer was inversely related to height, being 0.8 in taller women (greater than 165 cm) compared with women 155 cm tall or less; the trend in risk, although not constantly decreasing, was statistically significant (p trend = 0.03). A direct, statistically significant association emerged with weight and indices of body mass and post-menopausal breast cancer risk. Considering 2 indices of body weight (W/H2 and W/H1.5) and relative to thinner women, the respective estimated risks of post-menopausal breast cancer increased to 1.4 and 1.3 for grossly obese women, and the corresponding p values for trend were respectively 0.002 and 0.02. The role of overweight was more evident in women with early age at menopause, thus suggesting a duration-risk effect.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0020-7136
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
397-402
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pubmed:dateRevised |
2007-7-24
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pubmed:meshHeading |
pubmed-meshheading:2307528-Adult,
pubmed-meshheading:2307528-Aged,
pubmed-meshheading:2307528-Body Height,
pubmed-meshheading:2307528-Body Mass Index,
pubmed-meshheading:2307528-Body Weight,
pubmed-meshheading:2307528-Breast Neoplasms,
pubmed-meshheading:2307528-Case-Control Studies,
pubmed-meshheading:2307528-Female,
pubmed-meshheading:2307528-Humans,
pubmed-meshheading:2307528-Italy,
pubmed-meshheading:2307528-Menopause,
pubmed-meshheading:2307528-Middle Aged,
pubmed-meshheading:2307528-Risk Factors
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pubmed:year |
1990
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pubmed:articleTitle |
Anthropometric variables and risk of breast cancer.
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pubmed:affiliation |
Instituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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