rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
1980-3-27
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pubmed:abstractText |
The avian sarcoma virus transforming gene product pp60src has been partially purified by using ion exchange or immunoaffinity chromatography. These preparations contain a cyclic AMP-independent protein kinase activity capable of transferring radiolabel from [gamma-32P]ATP to immune rabbit IgG, casein, and the heavy chain purified from normal rabbit IgG. The casein kinase activity is specifically inhibited by anti-pp60src IgG. Comparison of the pp60src-protein kinase isolated from cells transformed by a wild-type ASV or by an ASV temperature-sensitive transformation mutant revealed that the latter product had a half-life of 3 min at 41 degrees C whereas that of the wild-type product was 20 min.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-1102604,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-195741,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-198667,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-200926,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-205879,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-206909,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-209218,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-210399,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-214242,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-218225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-219258,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-225522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-38740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-4331732,
http://linkedlifedata.com/resource/pubmed/commentcorrection/230504-4850204
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0027-8424
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6260-4
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:230504-Animals,
pubmed-meshheading:230504-Avian leukosis virus,
pubmed-meshheading:230504-Cell Transformation, Viral,
pubmed-meshheading:230504-Cyclic AMP,
pubmed-meshheading:230504-Immunoglobulin G,
pubmed-meshheading:230504-Mutation,
pubmed-meshheading:230504-Protein Kinases,
pubmed-meshheading:230504-Sarcoma, Experimental,
pubmed-meshheading:230504-Temperature,
pubmed-meshheading:230504-Viral Proteins
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pubmed:year |
1979
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pubmed:articleTitle |
Evidence that the avian sarcoma virus transforming gene product is a cyclic AMP-independent protein kinase.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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