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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1990-3-15
|
| pubmed:abstractText |
A feasibility study was undertaken prospectively to identify early clinical and laboratory factors predictive of acute hospital mortality in patients with the acquired immunodeficiency syndrome and concurrent Pneumocystis carinii pneumonia. Twenty-six patients hospitalized with bronchoscopy-proved P carinii pneumonia were studied. Nineteen patients survived their episode of P carinii pneumonia, while 7 subjects did not. The only clinical factor associated with mortality was a history of a shorter duration of pulmonary symptoms. Univariate analysis showed decreased total CD8 cell count, total lymphocyte count, serum hemoglobin, serum albumin, total thyroxine, and total triiodothyronine values consistent with a poor outcome. Multivariate logistic regression analysis showed that the single best prognostic indicator of acute mortality appeared to be a total serum triiodothyronine value less than 0.70 nmol/L obtained early in the hospital course, and that the combination of serum triiodothyronine and hemoglobin values provided a better indication for survival. These preliminary observations would appear to justify the further exploration of serial serum triiodothyronine measurements as a potentially valuable prognostic indicator for the treatment of patients with acquired immunodeficiency syndrome infected with P carinii and possibly other intercurrent infectious illnesses.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Hemoglobins,
http://linkedlifedata.com/resource/pubmed/chemical/L-Lactate Dehydrogenase,
http://linkedlifedata.com/resource/pubmed/chemical/Oxygen,
http://linkedlifedata.com/resource/pubmed/chemical/Serum Albumin,
http://linkedlifedata.com/resource/pubmed/chemical/Thyroid Hormones,
http://linkedlifedata.com/resource/pubmed/chemical/Triiodothyronine
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0003-9926
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
150
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
406-9
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:2302016-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:2302016-Adult,
pubmed-meshheading:2302016-Feasibility Studies,
pubmed-meshheading:2302016-Female,
pubmed-meshheading:2302016-Hemoglobins,
pubmed-meshheading:2302016-Humans,
pubmed-meshheading:2302016-L-Lactate Dehydrogenase,
pubmed-meshheading:2302016-Lymphopenia,
pubmed-meshheading:2302016-Male,
pubmed-meshheading:2302016-Middle Aged,
pubmed-meshheading:2302016-Oxygen,
pubmed-meshheading:2302016-Pneumonia, Pneumocystis,
pubmed-meshheading:2302016-Predictive Value of Tests,
pubmed-meshheading:2302016-Prognosis,
pubmed-meshheading:2302016-Prospective Studies,
pubmed-meshheading:2302016-Serum Albumin,
pubmed-meshheading:2302016-Thyroid Hormones,
pubmed-meshheading:2302016-Triiodothyronine
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Serum triiodothyronine values. Prognostic indicators of acute mortality due to Pneumocystis carinii pneumonia associated with the acquired immunodeficiency syndrome.
|
| pubmed:affiliation |
Section of Pulmonary/Critical Care Medicine, University of Southern California School of Medicine, Los Angeles 90033.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|