Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1980-2-15
|
| pubmed:abstractText |
The effectiveness of enteral and parenteral feeding in supporting a satisfactory nutritional status and/or reversing protein-energy malnutrition was evaluated in 28 children, ages 1-19 (14 female) with advanced malignant disease (21 solid tumors, 7 leukemia-lymphoma). At the onset of treatment, 21 patients received intensive nutritional counseling (INC) and oral supplementation while seven received total parenteral nutrition (TPN). Sixteen of 21 patients who received INC had a decreased intake (x 48 +/- 24%) Recommended Dietary Allowances (RDA) for kilocalories and dramatic weight loss (x 16.4 +/- 12.4%). A total of 18 patients received TPN for a mean of 24 days (7-60); kcal averaged 90 +/- 26% RDA during weight gain. At onset of TPN, the mean serum albumin, transferrin and total lymphocyte counts were 3.06 +/- 0.38 g/dl, 175 +/- 62 mg/dl, and 1102 +/- 966/mm3 respectively, 15/18 children had subnormal anthropometric measurements and 17/18 patients were anergic to recall skin test antigens. TPN for less than 9-14 days neither repleted weight, skinfold reserves, nor serum albumin concentrations (greater than 3.2 g/dl) although an early increase (p less than .02) in transferrin concentration was observed. However, TPN for 28 days supported weight gain (3.27 kg, 16 +/- 6%), increased serum albumin (0.62 +/- 0.43 g/dl, p less than .001) and transferrin (62 +/- 42, p less than .002) to normal concentrations and reversed anergy in 7/11 patients retested. This study documents the severity of protein energy malnutrition which accompanies intense treatment of children with cancer and the nutritional and immunological benefits of a 28 day course of TPN.
|
| pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-1066957,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-106932,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-142452,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-364722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-405096,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-405100,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-4852074,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-617404,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-798420,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-820290,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-861953,
http://linkedlifedata.com/resource/pubmed/commentcorrection/229780-99235
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
0003-4932
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
190
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
771-81
|
| pubmed:dateRevised |
2011-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:229780-Adolescent,
pubmed-meshheading:229780-Adult,
pubmed-meshheading:229780-Child, Preschool,
pubmed-meshheading:229780-Female,
pubmed-meshheading:229780-Hodgkin Disease,
pubmed-meshheading:229780-Humans,
pubmed-meshheading:229780-Infant,
pubmed-meshheading:229780-Leukemia,
pubmed-meshheading:229780-Lymphoma,
pubmed-meshheading:229780-Neoplasm Metastasis,
pubmed-meshheading:229780-Neoplasms,
pubmed-meshheading:229780-Neuroblastoma,
pubmed-meshheading:229780-Parenteral Nutrition, Total,
pubmed-meshheading:229780-Protein-Energy Malnutrition,
pubmed-meshheading:229780-Rhabdomyosarcoma,
pubmed-meshheading:229780-Sarcoma, Ewing,
pubmed-meshheading:229780-Teratoma,
pubmed-meshheading:229780-Wilms Tumor
|
| pubmed:year |
1979
|
| pubmed:articleTitle |
Reversal of protein-energy malnutrition in children during treatment of advanced neoplastic disease.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|