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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1980-2-26
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pubmed:abstractText |
Circulation levels of estrone sulfate (E1S) and dehydroepiandrosterone sulfate (DHAS) have been measured in plasma using a radioimmunoassay for estrone and dehydroepiandrosterone following extraction and hydrolysis of the sulfate. The mean +/- SE concentrations of E1S and DHAS in normal men were 458 +/- 25 pg/ml and 1.45 +/- 0.19 micrograms/ml, respectively. In normal women the values for days 5-7 of the cycle were 880 +/- 117 pg/ml and 1.25 +/- 0.12 micrograms/ml which were not different than the values for days 20-22 of 1195 +/- 176 pg/ml and 1.58 +/- 0.29 micrograms/ml. The mean values in post-menopausal women were 250 +/- 33 pg/ml and 0.47 +/- 0.07 micrograms/ml, both lower than the values in young women. In a group of cirrhotic men the mean values were 325 +/- 55 pg/ml and 0.38 +/- 0.12 micrograms/ml, both significantly lower than the normal values. This suggests a defect in sulfurylation in men with hepatic cirrhosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0039-128X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
563-73
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:229590-Adult,
pubmed-meshheading:229590-Aged,
pubmed-meshheading:229590-Dehydroepiandrosterone,
pubmed-meshheading:229590-Estrogens, Conjugated (USP),
pubmed-meshheading:229590-Estrone,
pubmed-meshheading:229590-Female,
pubmed-meshheading:229590-Humans,
pubmed-meshheading:229590-Liver Cirrhosis,
pubmed-meshheading:229590-Male,
pubmed-meshheading:229590-Menopause,
pubmed-meshheading:229590-Middle Aged,
pubmed-meshheading:229590-Radioimmunoassay,
pubmed-meshheading:229590-Sulfuric Acids
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pubmed:year |
1979
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pubmed:articleTitle |
Estrone sulfate and dehydroepiandrosterone sulfate concentrations in normal subjects and men with cirrhosis.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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