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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1990-2-7
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pubmed:abstractText |
Data were collected on 176 consecutive cases of drug overdose evaluated in an emergency department. Quantitative serum toxic screening (TS) was performed for 164 (93%) of these patients; positive results were noted for 133 patients (81%). Six classes of drugs (ethanol, benzodiazepines, salicylates, acetaminophen, barbiturates, and tricyclic antidepressants) were responsible for nearly 70% of all drug detections and were associated with 80% of all admissions in this patient sample. Only two patients (1%) had drug-specific treatment initiated because of TS results. In 12 patients (7%), TS confirmed substances for which specific treatments had been initiated on clinical grounds. Four patients (2%) had drug-specific treatment discontinued because of TS results. Thirty-two patients (19%) were admitted to a medical service; however, only seven patients (4%) were admitted primarily because of TS results. All other patients were admitted because of clinical abnormalities that required inpatient care. It is concluded that only a few drugs are responsible for most drug overdoses. Moreover, TS results rarely change the treatment or disposition of overdose patients; these decisions are typically based on clinical parameters.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acetaminophen,
http://linkedlifedata.com/resource/pubmed/chemical/Antidepressive Agents, Tricyclic,
http://linkedlifedata.com/resource/pubmed/chemical/Barbiturates,
http://linkedlifedata.com/resource/pubmed/chemical/Diazepam,
http://linkedlifedata.com/resource/pubmed/chemical/Salicylates
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0735-6757
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
16-22
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2293827-Acetaminophen,
pubmed-meshheading:2293827-Alcoholic Intoxication,
pubmed-meshheading:2293827-Antidepressive Agents, Tricyclic,
pubmed-meshheading:2293827-Barbiturates,
pubmed-meshheading:2293827-Blood Chemical Analysis,
pubmed-meshheading:2293827-Diazepam,
pubmed-meshheading:2293827-Emergencies,
pubmed-meshheading:2293827-Humans,
pubmed-meshheading:2293827-Overdose,
pubmed-meshheading:2293827-Retrospective Studies,
pubmed-meshheading:2293827-Salicylates
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pubmed:year |
1990
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pubmed:articleTitle |
Quantitative serum toxic screening in the management of suspected drug overdose.
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pubmed:affiliation |
Emergency Services Department, Massachusetts General Hospital, Boston 02114.
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pubmed:publicationType |
Journal Article
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