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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
14
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pubmed:dateCreated |
1991-4-8
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pubmed:abstractText |
Concentrates of erythrocytes without buffy coat, re-suspended in a newly developed electrolyte-containing re-suspension solution (SAG-S) poor in saccharose (30 mmol/l) are in vitro compared with commercial CDS-AG RCC. In the equivalence of biochemical parameters complex-haematological indicators show a significantly improved maintenance of the cell integrity in the new preparation of blood constituents up to a storage time of 35 days. By means of an in-vitro-technique we calculated for these SAG-S-erythrocytes a post-transfusional survival rate of 74%. In contrast to this the in-vivo survival rate for 20-day-old CDS-AG-cells was only 65% In the practically equivalent content of erythrocytes the preparations differ as to their purity. The saccharose concentration of 200 mmol/l presented in the CDS-AG medium has, as it is made evident, a stabilizing effect on the leukocytes, i.e. it is retarding the time-dependent WBC-destruction. The results of the clinical test step III confirm a good tolerability of the SAG-S RCC. By lacking possibilities of the comparison of equivalent (produced under the same preparation and storage conditions) concentrates of erythrocytes the higher transfusion efficiency of the SAG-S concentrates of erythrocytes to be expected could not be verified.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenine,
http://linkedlifedata.com/resource/pubmed/chemical/Citrates,
http://linkedlifedata.com/resource/pubmed/chemical/Citric Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Guanosine,
http://linkedlifedata.com/resource/pubmed/chemical/Sodium Chloride,
http://linkedlifedata.com/resource/pubmed/chemical/Sucrose
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0044-2542
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
406-10
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2293514-Adenine,
pubmed-meshheading:2293514-Blood Preservation,
pubmed-meshheading:2293514-Blood Transfusion,
pubmed-meshheading:2293514-Citrates,
pubmed-meshheading:2293514-Citric Acid,
pubmed-meshheading:2293514-Erythrocyte Transfusion,
pubmed-meshheading:2293514-Erythrocytes,
pubmed-meshheading:2293514-Glucose,
pubmed-meshheading:2293514-Guanosine,
pubmed-meshheading:2293514-Humans,
pubmed-meshheading:2293514-Sodium Chloride,
pubmed-meshheading:2293514-Sucrose
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pubmed:year |
1990
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pubmed:articleTitle |
[SAG-S solution--a new medium for the resuspension of erythrocyte concentrates].
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pubmed:affiliation |
Bezirksblutspendezentrale Zwickau.
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
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