Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
1991-4-8
pubmed:abstractText
Concentrates of erythrocytes without buffy coat, re-suspended in a newly developed electrolyte-containing re-suspension solution (SAG-S) poor in saccharose (30 mmol/l) are in vitro compared with commercial CDS-AG RCC. In the equivalence of biochemical parameters complex-haematological indicators show a significantly improved maintenance of the cell integrity in the new preparation of blood constituents up to a storage time of 35 days. By means of an in-vitro-technique we calculated for these SAG-S-erythrocytes a post-transfusional survival rate of 74%. In contrast to this the in-vivo survival rate for 20-day-old CDS-AG-cells was only 65% In the practically equivalent content of erythrocytes the preparations differ as to their purity. The saccharose concentration of 200 mmol/l presented in the CDS-AG medium has, as it is made evident, a stabilizing effect on the leukocytes, i.e. it is retarding the time-dependent WBC-destruction. The results of the clinical test step III confirm a good tolerability of the SAG-S RCC. By lacking possibilities of the comparison of equivalent (produced under the same preparation and storage conditions) concentrates of erythrocytes the higher transfusion efficiency of the SAG-S concentrates of erythrocytes to be expected could not be verified.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0044-2542
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
406-10
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[SAG-S solution--a new medium for the resuspension of erythrocyte concentrates].
pubmed:affiliation
Bezirksblutspendezentrale Zwickau.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract