Linked Life Data

2293226

Source:http://linkedlifedata.com/resource/pubmed/id/2293226

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-4-9
pubmed:abstractText
The immunopotentiating effects of the traditional Chinese drugs Ginsenoside (GS) and Glycyrrhiza polysaccharide (GPS) are reported. It was demonstrated that GS promotes the phagocytic activity of plaque-forming cells (PFC) and enhances the mitogenesis of T and B lymphocytes primed by mitogens. The mechanism of these effects is related to the ratio of cGMP to cAMP. GS also plays a role in the NKC-IFN-IL-2 regulatory system, inhibits the growth of tumor cells, and antagonizes the suppression of ADCC and NK cytotoxicities in mice with surgical stress. GS exhibits bidirectional effects on immunological functions. GPS increases the phagocytosis of macrophages, induces macrophages to secret IL-1, enhances both NK and ADCC activities, behaves as a mitogen of B lymphocytes, inhibits the multiplication of several viruses, and induces the release of IFN from spleen cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0258-8757
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
188-93
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Immunopotentiating effect of traditional Chinese drugs--ginsenoside and glycyrrhiza polysaccharide.
pubmed:affiliation
Norman Bethune University of Medical Sciences, Changchun.
pubmed:publicationType
Journal Article, Review