Linked Life Data

2290067

Source:http://linkedlifedata.com/resource/pubmed/id/2290067

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-4-3
pubmed:abstractText
Data is presented to support a physiologic vasoconstrictor function of the parasympathetic nervous system in the anterior uvea of the eye. Studies in rabbits, cats and monkeys demonstrate that stimulation of the parasympathetic nerve fibers running with the oculomotor nerve to the eye induces a reduction in blood flow of the iris and in rabbits in the ciliary processes in addition. Pharmacologic blocking experiments indicate that most of this phenomenon is based on a cholinergic component. Since at least in rabbits mechanical factors such as stretching of the iridial tissue, a steeling phenomenon to nearby tissues of blood as well as secondary effects caused by changes in the intraocular pressure can be excluded, the reduction in blood flow in all likelihood reflects a true vasoconstriction. Experiments in unanesthetized rabbits indicate that there is a continuous physiologic cholinergic vasoconstrictor tone in the iris and ciliary processes normally. Thus, the anterior uvea in mammals may be one of the tissues exhibiting a cholinergic vasoconstriction phenomenon, found more commonly in lower vertebrates.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
8756-3320
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
195-202
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Cholinergic vasoconstriction in the eye.
pubmed:affiliation
Glaucoma Research Laboratories, Pharmacia Ophthalmics AB, Uppsala, Sweden.
pubmed:publicationType
Journal Article, Review