Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1991-4-1
pubmed:abstractText
Although it is well established that increases in tryptophan availability can increase brain serotonin synthesis, the effect of tryptophan loads on serotonin release is not as clear. We have used in vivo microdialysis in order to monitor extracellular serotonin in the lateral hypothalamus to examine this issue. Tryptophan methyl ester (100 mg/kg IP) was administered to ad lib-fed and 48-h food-deprived rats. The results suggest that a peripheral tryptophan load can elevate extracellular serotonin in food-deprived subjects more effectively than in food-replete subjects.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0361-9230
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
803-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Tryptophan increases extracellular serotonin in the lateral hypothalamus of food-deprived rats.
pubmed:affiliation
Department of Psychology, Princeton University, NJ 08544-1010.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't