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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-3-25
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pubmed:abstractText |
A DNA fragment size variant for the growth hormone gene, Gh, has been identified among inbred strains of mice. The inbred strains SM/J and CAST/Ei carry the less frequent allele Ghb and 11 other strains carry the Gha allele. Segregation analysis of data from two crosses involving SM/J and NZB/BINJ and a cross involving BALB/cJ and CAST/Ei confirmed the assignment of Gh to mouse chromosome 11 and placed the locus 2.6 +/- 1.8 map units distal to Erba (avian erythroblastosis oncogene A), a position consistent with the assignment of the Gh locus to the q22-q24 region of chromosome 17 on the human map. Segregation analysis also refined the location of Sparc (secreted acidic cysteine-rich glycoprotein) on mouse chromosome 11 to a position 16.7 +/- 4.2 map units proximal to Evi-2 (ecotropic viral integration site 2).
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0888-7543
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:geneSymbol |
Es-3,
Evi-2,
Gh<up>a</up>,
Gh<up>b</up>,
Hba,
Sparc
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
591-4
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2286379-Alleles,
pubmed-meshheading:2286379-Animals,
pubmed-meshheading:2286379-Chromosome Mapping,
pubmed-meshheading:2286379-Crosses, Genetic,
pubmed-meshheading:2286379-Female,
pubmed-meshheading:2286379-Genetic Markers,
pubmed-meshheading:2286379-Growth Hormone,
pubmed-meshheading:2286379-Humans,
pubmed-meshheading:2286379-Male,
pubmed-meshheading:2286379-Mice,
pubmed-meshheading:2286379-Mice, Inbred Strains,
pubmed-meshheading:2286379-Recombination, Genetic,
pubmed-meshheading:2286379-Species Specificity
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pubmed:year |
1990
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pubmed:articleTitle |
Localization of the growth hormone gene to the distal half of mouse chromosome 11.
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pubmed:affiliation |
Department of Molecular and Cellular Biology, Roswell Park Memorial Institute, New York State Department of Health, Buffalo 14263.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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