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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
3
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pubmed:dateCreated |
1991-3-18
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|
pubmed:abstractText |
The effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin (ppDNM) on the lectin binding to HIV-1 glycoprotein was analyzed by using biotinylated lectins of various sugar specificities as probes. ppDNM potentially inhibited HIV-1-induced syncytium formation and viral infectivity of HIV-1 without cytotoxicity. The lectin binding assay showed that ppDNM treatment reduced Con A binding to gp120 of HIV-1.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Jun
|
|
pubmed:issn |
0021-5112
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
75-87
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2283726-1-Deoxynojirimycin,
pubmed-meshheading:2283726-Antiviral Agents,
pubmed-meshheading:2283726-Cell Line,
pubmed-meshheading:2283726-Concanavalin A,
pubmed-meshheading:2283726-Glucosamine,
pubmed-meshheading:2283726-HIV Envelope Protein gp120,
pubmed-meshheading:2283726-HIV-1,
pubmed-meshheading:2283726-Humans,
pubmed-meshheading:2283726-Lectins,
pubmed-meshheading:2283726-Molecular Structure,
pubmed-meshheading:2283726-Oligosaccharides
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|
pubmed:year |
1990
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|
pubmed:articleTitle |
Effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin on the lectin binding to HIV-1 glycoproteins.
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pubmed:affiliation |
AIDS Research Center, National Institute of Health, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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