Linked Life Data

2280840

Source:http://linkedlifedata.com/resource/pubmed/id/2280840

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-3-8
pubmed:abstractText
Teflon is utilized in neurosurgery as well as in plastic, vascular and heart surgery. Although the effect of Teflon on different types of cells and tissues has been previously studied, we are not aware of any study in which the effect of Teflon was tested on cells of the central nervous system. We have therefore examined the tissue compatibility of spongy and fibrous Teflon by directly exposing the Teflon to dissociated cerebellar cells containing both glia and neurons in tissue culture. Daily examination of the growth of the cells adjacent to Teflon fibers using an inverted phase contrast microscope revealed that Teflon has little or no effect on the growth of these cells. When the cells are fixed after 7 days in culture and stained by the Jenner-Giemsa method, adhesion of both glia and neurons to the surface of the Teflon was seen. Attachment of neural cells to the Teflon was not extensive, as was shown by indirect immunofluorescence technique in connection with double-label staining with antiGFAP as glia marker and anti-M6 as mouse neuron marker. Thus, these experiments show that Teflon is relatively inert when used as an implant in the central nervous system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0344-5607
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
299-303
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Neural tissue compatibility of Teflon as an implant material for microvascular decompression.
pubmed:affiliation
Department of Neurosurgery, College of Medicine and Medical Sciences, King Faisal University, Dammam, Saudi Arabia.
pubmed:publicationType
Journal Article