Linked Life Data

227935

Source:http://linkedlifedata.com/resource/pubmed/id/227935

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:227935rdf:typepubmed:Citationlld:pubmed
pubmed-article:227935lifeskim:mentionsumls-concept:C0330390lld:lifeskim
pubmed-article:227935lifeskim:mentionsumls-concept:C0012984lld:lifeskim
pubmed-article:227935lifeskim:mentionsumls-concept:C0027061lld:lifeskim
pubmed-article:227935lifeskim:mentionsumls-concept:C0034792lld:lifeskim
pubmed-article:227935lifeskim:mentionsumls-concept:C0022116lld:lifeskim
pubmed-article:227935lifeskim:mentionsumls-concept:C1280500lld:lifeskim
pubmed-article:227935lifeskim:mentionsumls-concept:C0599756lld:lifeskim
pubmed-article:227935pubmed:issue5lld:pubmed
pubmed-article:227935pubmed:dateCreated1980-1-28lld:pubmed
pubmed-article:227935pubmed:abstractTextExperimental myocardial ischemia produced in dogs by proximal left anterior descending coronary artery ligation is accompanied by relatively rapid (1 h) increases in the number of (-) [3H]dihydroalprenolol binding sites without changing their dissociation constants in ischemic left ventricular tissue. The changes, persist for at least 8 h and are accompanied by marked decreases in myocardial tissue ischemic region norepinephrine content. In contrast, in the same canine model 1 h of proximal left anterior descending coronary artery ligation did not result in a significant change in the number of [3H]quinuclidynl benzilate binding sites of their dissociation constants. However, the number of [3H]quinuclidynl benzilate binding sites (muscarinic cholinergic receptors) are 50--70% greater than (-) [3H]dihydroalprenolol binding sites (beta adrenergic receptors) in canine left ventricular tissue. Thus, the data suggest that proximal left anterior descending coronary artery occlusion for 1 h significantly increases the number of beta adrenergic receptors in ischemic left ventricular tissue without changing the number of muscarinic cholinergic receptors. Whether the ischemia-produced increase in cardiac beta-receptor content is causally related to increased cyclic AMP levels that develop in ischemic tissue and/or an etiologic factor in arrhythmias originating from ischemic myocardial tissue will have to be determined in additional studies.lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:languageenglld:pubmed
pubmed-article:227935pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:citationSubsetAIMlld:pubmed
pubmed-article:227935pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:227935pubmed:statusMEDLINElld:pubmed
pubmed-article:227935pubmed:monthNovlld:pubmed
pubmed-article:227935pubmed:issn0021-9738lld:pubmed
pubmed-article:227935pubmed:authorpubmed-author:LefkowitzR...lld:pubmed
pubmed-article:227935pubmed:authorpubmed-author:WongT MTMlld:pubmed
pubmed-article:227935pubmed:authorpubmed-author:WillersonJ...lld:pubmed
pubmed-article:227935pubmed:authorpubmed-author:MukherjeeAAlld:pubmed
pubmed-article:227935pubmed:authorpubmed-author:BujaL MLMlld:pubmed
pubmed-article:227935pubmed:issnTypePrintlld:pubmed
pubmed-article:227935pubmed:volume64lld:pubmed
pubmed-article:227935pubmed:ownerNLMlld:pubmed
pubmed-article:227935pubmed:authorsCompleteYlld:pubmed
pubmed-article:227935pubmed:pagination1423-8lld:pubmed
pubmed-article:227935pubmed:dateRevised2009-11-18lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-A...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-M...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-D...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-C...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-F...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-M...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-N...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-C...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-L...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-R...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-R...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-R...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-R...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-D...lld:pubmed
pubmed-article:227935pubmed:meshHeadingpubmed-meshheading:227935-Q...lld:pubmed
pubmed-article:227935pubmed:year1979lld:pubmed
pubmed-article:227935pubmed:articleTitleBeta adrenergic and muscarinic cholinergic receptors in canine myocardium. Effects of ischemia.lld:pubmed
pubmed-article:227935pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:227935pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:227935lld:pubmed