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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-3-11
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pubmed:abstractText |
Cell kinetics was determined, as 3H-thymidine labeling index (LI), in hepatic lesions from 36 patients with primary colorectal carcinoma: LI values ranged from 0.9% to 23.5% and were normally distributed. Cell kinetics was not related to sex or age of the patient, or to liver function. For clinical studies the median LI value of 10% was used to separate slowly and rapidly proliferating lesions. Univariate analysis showed that patients radically resected and with a low LI tumor have a longer disease-free interval and a better probability of 12-month survival than those non-radically resected and with a high LI tumor. When treatment and cell kinetics were taken into consideration, the probability of 12-month survival was 100% for patients with slowly proliferating and radically resected hepatic metastases. Patients with rapidly proliferating tumors, regardless of type of treatment, had the worst prognosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0894-8569
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
135-43; discussion 143-4
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pubmed:dateRevised |
2008-11-20
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pubmed:meshHeading |
pubmed-meshheading:2278908-Adenocarcinoma,
pubmed-meshheading:2278908-Adult,
pubmed-meshheading:2278908-Aged,
pubmed-meshheading:2278908-Cell Cycle,
pubmed-meshheading:2278908-Colorectal Neoplasms,
pubmed-meshheading:2278908-Female,
pubmed-meshheading:2278908-Humans,
pubmed-meshheading:2278908-Liver Neoplasms,
pubmed-meshheading:2278908-Male,
pubmed-meshheading:2278908-Middle Aged,
pubmed-meshheading:2278908-Prognosis,
pubmed-meshheading:2278908-Tumor Cells, Cultured
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pubmed:year |
1990
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pubmed:articleTitle |
Cell kinetics of hepatic metastases as a prognostic marker in patients with advanced colorectal carcinoma.
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pubmed:affiliation |
Experimental Oncology C, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy.
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pubmed:publicationType |
Journal Article
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