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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1991-1-29
|
| pubmed:abstractText |
By DNA sequencing and gene dissection, it has been revealed that Su+UGA#11, the mutant prfB of E. coli (Chang et al., 1990) has a double mutation compared with the wild-type LS653: one is a base substitution from T to C at the codon 63 and the other is from G to A at the codon 79. Both mutations cause amino acid substitution, Leu63----Phe63 (L63F) and Asp79----Gly79 (D79G), and are necessary to confer the efficient UGA suppressor activity.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0021-504X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
65
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
115-9
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2275732-Base Sequence,
pubmed-meshheading:2275732-Codon,
pubmed-meshheading:2275732-DNA, Bacterial,
pubmed-meshheading:2275732-Escherichia coli,
pubmed-meshheading:2275732-Genes, Bacterial,
pubmed-meshheading:2275732-Molecular Sequence Data,
pubmed-meshheading:2275732-Mutation,
pubmed-meshheading:2275732-Peptide Termination Factors,
pubmed-meshheading:2275732-Suppression, Genetic
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Identification of the mutations in the prfB gene of Escherichia coli K12, which confer UGA suppressor activity.
|
| pubmed:affiliation |
Department of Biophysics, Faculty of Science, Kyoto University, Japan.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|