Linked Life Data

2274321

Source:http://linkedlifedata.com/resource/pubmed/id/2274321

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1991-2-22
pubmed:abstractText
Human nasal epithelial cells, which lost their cilia in monolayer cultures, redeveloped cilia after 1 week in a suspension culture system. Before ciliogenesis started, the number of microvilli increased. Primary cilia were absent. The different cytoplasmic stages of this in vitro ciliogenesis could be reconstructed here into a sequence of events comparable to that described in the embryogenesis of the mammalian respiratory tract. In addition to the fibrogranular aggregates, deuterosomes with procentrioles and kinetosomes, small tubular structures in the fibrogranular aggregates could be visualized. The formation of the ciliary shaft above an aligned basal body started as an elevation of the apical membrane without any recognizable axonemal ultrastructure. This study provides the first full description of in vitro ciliogenesis on a human tissue.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0301-1569
pubmed:author
pubmed:issnType
Print
pubmed:volume
52
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
368-74
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Ciliogenesis in cultured human nasal epithelium.
pubmed:affiliation
Center for Human Genetics, University of Leuven, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't