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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
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pubmed:dateCreated |
1991-2-22
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pubmed:abstractText |
We present data on the effects of three chromosome 17 deletions on transmission ratio distortion (TRD) and sterility of several t-haplotypes. All three deletions have similar effects on male TRD: that is, Tdel/tcomplete genotypes all transmit their t-haplotype in very high proportion. However, each deletion has different effects on sterility of heterozygous males, with TOr/t being fertile, Thp/t less fertile, and TOrl/t still less fertile. These data suggest that wild-type genes on chromosomes homologous to t-haplotypes can be important regulators of both TRD and fertility in males, and that the wild-type genes concerned with TRD and fertility are at least to some extent different. The data also provide a rough map of the positions of these genes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:author | |
pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
179-83
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2272508-Animals,
pubmed-meshheading:2272508-Chromosome Deletion,
pubmed-meshheading:2272508-Chromosome Mapping,
pubmed-meshheading:2272508-Female,
pubmed-meshheading:2272508-Genotype,
pubmed-meshheading:2272508-Haplotypes,
pubmed-meshheading:2272508-Infertility, Male,
pubmed-meshheading:2272508-Male,
pubmed-meshheading:2272508-Mice
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pubmed:articleTitle |
Deletion analysis of male sterility effects of t-haplotypes in the mouse.
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pubmed:affiliation |
Department of Zoology, University of Texas, Austin 78712-1064.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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