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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1991-2-20
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pubmed:abstractText |
In an attempt to overcome the lack of well characterized, inbred, and congenic strains, as well as a paucity of immunological reagents, in rabbit and rat models, we have developed a procedure for performing full-thickness, penetrating keratoplasty in the mouse. One hundred percent of isografts (BALB/c onto BALB/c) were successful, while 83.3% of allografts (C3H onto BALB/c) failed. The use of a mouse model to study corneal graft failure will allow a critical evaluation of the role of a variety of immunological mediators in causing graft failure.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-023X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
781-5
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:2270163-Animals,
pubmed-meshheading:2270163-Cornea,
pubmed-meshheading:2270163-Corneal Opacity,
pubmed-meshheading:2270163-Female,
pubmed-meshheading:2270163-Graft Rejection,
pubmed-meshheading:2270163-Keratoplasty, Penetrating,
pubmed-meshheading:2270163-Mice,
pubmed-meshheading:2270163-Mice, Inbred BALB C,
pubmed-meshheading:2270163-Mice, Inbred C3H,
pubmed-meshheading:2270163-Postoperative Complications,
pubmed-meshheading:2270163-Transplantation, Homologous,
pubmed-meshheading:2270163-Transplantation, Isogeneic
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pubmed:year |
1990
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pubmed:articleTitle |
A method for performing full-thickness, orthotopic, penetrating keratoplasty in the mouse.
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pubmed:affiliation |
Department of Ophthalmology, Southern Illinois University, School of Medicine, Springfield 62794-9230.
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pubmed:publicationType |
Journal Article
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