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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
1991-2-14
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pubmed:abstractText |
The shape of supercoiled DNA molecules in solution is directly visualized by cryo-electron microscopy of vitrified samples. We observe that: (i) supercoiled DNA molecules in solution adopt an interwound rather than a toroidal form, (ii) the diameter of the interwound superhelix changes from about 12 nm to 4 nm upon addition of magnesium salt to the solution and (iii) the partition of the linking deficit between twist and writhe can be quantitatively determined for individual molecules.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-1004545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-2359128,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-2538631,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-2591374,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-3039150,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-3043536,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-3160481,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-3656409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-3663849,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-4939039,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-6098522,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-6099256,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-6321743,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-6322001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2265618-6968450
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0261-4189
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4551-4
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1990
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pubmed:articleTitle |
Direct visualization of supercoiled DNA molecules in solution.
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pubmed:affiliation |
Laboratoire d'Analyse Ultrastructurale (LAU), Université de Lausanne, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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