Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1991-2-1
pubmed:abstractText
An examination of the effects of the diurnal cycle on phenylpropanolamine (PPA) anorexia was conducted using two groups of rats, differentiated on the basis of time (Night or Day) of drug injection (0, 10, 20, or 30 mg/kg PPA). The results demonstrate that PPA, over a range of doses, has greater anorectic potency during the dark phase of the diurnal cycle. Moreover, the effect of PPA on water intake was not influenced by the diurnal cycle, suggesting that the diurnal effect was limited to the inhibitory action of PPA on feeding. Other studies are cited which, combined with the present results, suggest that the diurnal cycle may modulate feeding control processes, and that the impact of an anorectic agent such as PPA on feeding behavior may be, in part, a function of the diurnal cycle.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
201-3
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Diurnal variation of phenylpropanolamine anorexia in rats.
pubmed:affiliation
Department of Psychology, Texas A&M University, College Station 77843.
pubmed:publicationType
Journal Article