Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1991-2-5
|
pubmed:abstractText |
We conducted a clinical investigation on the use of S6472, an sustained release preparation of cefaclor, in the dermatological area. Thirty-two patients serving as subjects were divided into group I (14 cases, including folliculitis and acne pustulora), group II (16 cases, including furuncle, furunculosis and carbuncle) and others (2 cases). One or 2 wrappers (375 or 750 mg) of S6472 were orally administered to patients twice daily after meals. In group I, the efficacy rate was 100%. Clinical results were as follows: Excellent (6 cases), good (8 cases), fair (0), and poor (0). In group II, the efficacy rate was 93.8%: Excellent (10 cases), good (5 cases), fair (1 case), and poor (0). A decrease of the bacteriological effect was observed in 1 case with Staphylococcus epidermidis. A superinfection was noted in 1 case Staphylococcus aureus. The causative bacteria were all eradicated in the remaining 24 cases. No side effects were detected. From the above results, S6472 appears to be a useful preparation, twice daily oral administration has excellent effects against dermatological infections.
|
pubmed:language |
jpn
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0368-2781
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
43
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1621-8
|
pubmed:dateRevised |
2009-11-11
|
pubmed:meshHeading |
pubmed-meshheading:2262967-Administration, Oral,
pubmed-meshheading:2262967-Adolescent,
pubmed-meshheading:2262967-Adult,
pubmed-meshheading:2262967-Bacteria,
pubmed-meshheading:2262967-Bacterial Infections,
pubmed-meshheading:2262967-Cefaclor,
pubmed-meshheading:2262967-Delayed-Action Preparations,
pubmed-meshheading:2262967-Drug Evaluation,
pubmed-meshheading:2262967-Female,
pubmed-meshheading:2262967-Humans,
pubmed-meshheading:2262967-Male,
pubmed-meshheading:2262967-Middle Aged,
pubmed-meshheading:2262967-Skin Diseases, Infectious
|
pubmed:year |
1990
|
pubmed:articleTitle |
[A clinical study on S6472, sustained release preparation of cefaclor, dermatological area].
|
pubmed:affiliation |
Department of Dermatology, Surugadai Nippon University Hospital.
|
pubmed:publicationType |
Journal Article,
English Abstract
|