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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
1991-2-1
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pubmed:abstractText |
Rate constants for the reactions of cumyl hydroperoxide and t-butyl hydroperoxide with ferrous complexes of ATP and citrate were measured at pH 7.4. These ligands are potential chelators of iron(II) in the low-molecular weight iron pool that may catalyze oxidative degradation of biomolecules. The second-order rate constants for the reduction of cumyl hydroperoxide and t-butyl hydroperoxide by ferrous ATP are 3.1 x 10(3) and 1.3 x 10(3) M-1.s-1, respectively, at 25 degrees C and 0.11 M ionic strength. Rates of reduction by ferrous citrate are similar. Activation enthalpies for these reactions average 10 kcal/mol.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0014-5793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
275
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
114-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
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pubmed:year |
1990
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pubmed:articleTitle |
Reactions of Fe(II)-ATP and Fe(II)-citrate complexes with t-butyl hydroperoxide and cumyl hydroperoxide.
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pubmed:affiliation |
Biodynamics Institute, Louisiana State University, Baton Rouge 70803-1804.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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