Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12 Suppl
pubmed:dateCreated
1991-1-29
pubmed:abstractText
In this article, we review and discuss the pathophysiology of brain ischemia, focusing on requirements of cerebral metabolism, biochemical characterization of the energy reserve, and autoradiographic and tomographic methods for in vivo evaluation of cerebral blood flow and metabolism. We propose new therapeutic strategies for the management of the acute phase of stroke, based on diagnostic protocols that include clinical evaluation, noninvasive study of neck and intracranial arteries, brain computed tomography, and single-photon emission computed tomography. The ideal therapeutic trial should combine early thrombolysis and active brain protection against those biochemical mechanisms leading to irreversible neuronal damage.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0039-2499
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
IV9-11
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Pathophysiology of ischemic brain disease.
pubmed:affiliation
Department of Neurological Sciences, University of Rome La Sapienza, Italy.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't