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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1991-1-31
|
| pubmed:abstractText |
Positron emission tomography of the brain following intravenous injection of (+) (R) and (-) (S) N-[11C-methyl]nicotine showed a marked reduced uptake of both isomers, especially the (R) form, in Alzheimer patients as compared to age-matched controls. The significantly larger difference between the uptake values of the (S)- and (R)-enantiomers of 11C-nicotine in Azheimer brains may be of diagnostic value.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0936-3076
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
215-24
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2257061-Aged,
pubmed-meshheading:2257061-Alzheimer Disease,
pubmed-meshheading:2257061-Brain,
pubmed-meshheading:2257061-Carbon Radioisotopes,
pubmed-meshheading:2257061-Humans,
pubmed-meshheading:2257061-Middle Aged,
pubmed-meshheading:2257061-Nicotine,
pubmed-meshheading:2257061-Stereoisomerism,
pubmed-meshheading:2257061-Tomography, Emission-Computed
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Decreased uptake and binding of 11C-nicotine in brain of Alzheimer patients as visualized by positron emission tomography.
|
| pubmed:affiliation |
Department of Pharmacology, University of Uppsala, Sweden.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|