Linked Life Data

2257025

Source:http://linkedlifedata.com/resource/pubmed/id/2257025

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-1-25
pubmed:abstractText
We have recorded 35 primary central nervous system (C.N.S.) lymphomas from 1982 to 1988 in Bordeaux in order to show their increasing frequency, and clinicopathological features. Mean age was 57 (15-81). Only one patient was immunocompromised. Clinical symptoms consisted mostly of focal neurologic deficits (23 cases) and mental disturbance (16 cases). Diagnosis was made on bioptic material (20 cases mostly stereotaxic), surgery (13 cases) or autopsy (2 cases). Lymphoma was localised in the brain with unifocal (50%), multifocal (30%) or diffuse (20%) involvement at computed tomographic scans. Histopathological features were diffuse infiltration of the cerebral tissue with perivascular clustering. Two particular cases were observed: one with mostly a perivascular pattern affecting the white matter of both cerebral hemisphere; another with amyloidosis deposits. According to Working Formulation, histologic types were of intermediate or high grade of malignancy (66%), with 35% large, non cleaved-cell (centroblastic) subtype. Immunochemistry on paraffin sections with UCHL-1, MB-2, LN-1, L-26 showed that 94% were of B-cell nature and only one probably of T-cell origin.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0242-6498
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
268-74
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
[Malignant primary non-Hodgkin's lymphoma of the central nervous system. Anatomo-clinical analysis of 35 cases].
pubmed:affiliation
Service d'Anatomopathologie, Hôpital Pellegrin, Bordeaux.
pubmed:publicationType
Journal Article, English Abstract, Review