Linked Life Data

2256811

Source:http://linkedlifedata.com/resource/pubmed/id/2256811

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
1991-1-22
pubmed:abstractText
Certain pharmacologic interventions may improve outcome for brain injury in animals and humans. Medications affecting the dopaminergic pathway appear to be important. We present the case of a 24-year-old man with traumatic brain injury who remained unresponsive to commands and unchanged for six months despite periodic aggressive therapy. Within days of beginning Sinemet (levodopa/carbidopa), the patient became conversant and responsive. The reported low likelihood of spontaneous recovery of cognition in patients who are vegetative for six months suggests that Sinemet was responsible for this patient's recovery. In this case, the relatively small risk of side effects from Sinemet was greatly outweighed by the change in functional outcome.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0003-9993
pubmed:author
pubmed:issnType
Print
pubmed:volume
71
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1081-3
pubmed:dateRevised
2009-10-6
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Recovery from vegetative state of six months' duration associated with Sinemet (levodopa/carbidopa).
pubmed:affiliation
Department of Orthopaedics and Rehabilitation, University of Vermont, Burlington.
pubmed:publicationType
Journal Article, Case Reports