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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1991-1-24
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pubmed:databankReference |
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pubmed:abstractText |
The complete primary structure of a bovine-brain-derived inhibitor of protein kinase C has been established. Fragments of the purified protein were obtained by cleavage with cyanogen bromide, Staphylococcus aureus V8 protease, trypsin and chymotrypsin. Subsequent analysis of the resulting fragments by fast-atom-bombardment mass spectrometry and Edman degradation revealed a calculated molecular mass of 11,779 Da with the following 107-amino-acid sequence: [sequence: see text] This inhibitor does not share significant primary structural identity with any other known protein.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0014-2956
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
194
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
19-23
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:2253615-Amino Acid Sequence,
pubmed-meshheading:2253615-Animals,
pubmed-meshheading:2253615-Brain,
pubmed-meshheading:2253615-Cattle,
pubmed-meshheading:2253615-Chymotrypsin,
pubmed-meshheading:2253615-Cyanogen Bromide,
pubmed-meshheading:2253615-Enzyme Inhibitors,
pubmed-meshheading:2253615-Mass Spectrometry,
pubmed-meshheading:2253615-Molecular Sequence Data,
pubmed-meshheading:2253615-Peptide Fragments,
pubmed-meshheading:2253615-Protein Kinase C,
pubmed-meshheading:2253615-Trypsin
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pubmed:year |
1990
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pubmed:articleTitle |
Amino acid sequence of a 12-kDa inhibitor of protein kinase C.
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pubmed:affiliation |
Biochemistry Department, Upjohn Laboratories, Kalamazoo, MI 49001.
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pubmed:publicationType |
Journal Article,
Retracted Publication,
Research Support, Non-U.S. Gov't
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