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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1991-1-16
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pubmed:abstractText |
The dynamics of the formation of postvaccinal immunity after immunization with preparations obtained with the use of hydroxylamine (HA) preparations from Proteus strains of different O serogroups, Salmonella minnesota Re-mutant and the common antimicrobial antigen isolated from Escherichia coli 14 has been studied on mice with Proteus peritonitis-bacteremia used as a model. The study has revealed that intraperitoneal immunization with Proteus HA preparations stimulates the phagocytic activity of peritoneal mononuclear cells in mice and induces an increase in the titers of specific O antibodies. Proteus antigens ensure the formation of anti-Proteus immunity, preventing the death of the animals from peritonitis-bacteremia. The protection of mice from such infection resulting from the injection of the common antigens of gram-negative bacteria is considerably less. These data are indicative of the possibility of using Proteus peritonitis-bacteremia as a model for the study of the protective potency of Proteus vaccines.
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pubmed:language |
rus
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0372-9311
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
74-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2251896-Animals,
pubmed-meshheading:2251896-Antibodies, Bacterial,
pubmed-meshheading:2251896-Antibody Specificity,
pubmed-meshheading:2251896-Bacterial Vaccines,
pubmed-meshheading:2251896-Disease Models, Animal,
pubmed-meshheading:2251896-Escherichia coli,
pubmed-meshheading:2251896-Immunity,
pubmed-meshheading:2251896-Immunization,
pubmed-meshheading:2251896-Mice,
pubmed-meshheading:2251896-Peritonitis,
pubmed-meshheading:2251896-Proteus Infections,
pubmed-meshheading:2251896-Proteus mirabilis,
pubmed-meshheading:2251896-Proteus vulgaris,
pubmed-meshheading:2251896-Salmonella,
pubmed-meshheading:2251896-Sepsis,
pubmed-meshheading:2251896-Staphylococcus aureus,
pubmed-meshheading:2251896-Time Factors
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pubmed:year |
1990
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pubmed:articleTitle |
[Proteus peritonitis-bacteremia in mice--a model for studying postvaccinal Proteus immunity].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|