Linked Life Data

2250079

Source:http://linkedlifedata.com/resource/pubmed/id/2250079

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1991-1-14
pubmed:abstractText
The present study was undertaken to compare the periodontal status of a group of 50 patients on long-term non-steroidal anti-inflammatory drug (NSAID) therapy with that of an age and sex-matched group of 42 controls. The mean duration of drug therapy in the study group was 9 years (range 2-30 years). The clinical parameters investigated were plaque index (PI), gingival index (GI), pocket probing depth (PPD), loss of attachment (LOA), gingival recession (GR) and gingival fluid flow (GFF). Long cone periapical radiographs were also taken to score the amount of alveolar bone resorption. Examinations were carried out on 6 Ramfjord teeth in each subject. The results showed that there were no significant differences between the groups for PI, GI, PPD, LOA, GR or alveolar bone resorption. However, a highly significant difference was seen between the gingival fluid flow in the study (16.74 +/- 10.61) and control (37.72 +/- 28.63) groups (p less than 0.001). It is suggested that this may be associated with the specific effects of NSAIDs in reducing the vascularity and permeability of small blood vessels.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0303-6979
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
654-8
pubmed:dateRevised
2006-10-30
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
An association between long-term non-steroidal anti-inflammatory drug therapy and the severity of periodontal disease.
pubmed:affiliation
Department of Operative Dentistry, Dental School, Newcastle-upon-Tyne, UK.
pubmed:publicationType
Journal Article