Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1991-1-9
|
| pubmed:abstractText |
Despite extensive investigation, the mechanisms of host resistance against C. albicans infection remain poorly understood. Granulocytes and macrophages are the major effector cell types; however, their intrinsic candidacidal activity is rather limited, and its full expression requires augmentation by components of the T cell-initiated lymphokine cascade. Consequently, susceptibility to recurrent mucocutaneous infections may be associated with aberrant T cell function. In contrast, protection from systemic infection appears to be mediated by candida-specific antibodies.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0344-0338
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
186
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
527-34
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:2247381-Candida albicans,
pubmed-meshheading:2247381-Candidiasis,
pubmed-meshheading:2247381-Humans,
pubmed-meshheading:2247381-Immunity, Cellular,
pubmed-meshheading:2247381-Immunity, Innate,
pubmed-meshheading:2247381-Macrophages,
pubmed-meshheading:2247381-Recurrence,
pubmed-meshheading:2247381-Symbiosis
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
What's new in the mechanisms of host resistance to Candida albicans infection?
|
| pubmed:affiliation |
Department of Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands.
|
| pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|