Linked Life Data

224454

Source:http://linkedlifedata.com/resource/pubmed/id/224454

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4409
pubmed:dateCreated
1979-10-17
pubmed:abstractText
The incidence of trigeminal ganglion infection after corneal inoculation of guinea pigs with thymidine kinase-negative mutants of herpes simplex virus was markedly reduced compared to infection after inoculation of thymidine kinase-positive virus. Thymidine kinase-negative herpes simplex virus replicated well in ocular tissues in which dividing or potentially dividing cells were present, but not in trigeminal ganglion infection of nondividing neurons. Thymidine kinase-positive virus, however, replicated well in ocular tissues as well as in trigeminal ganglion. These results suggest that thymidine kinase expression of herpes simplex virus may be important in infections of sensory ganglia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
31
pubmed:volume
205
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
915-7
pubmed:dateRevised
2007-3-19
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Trigeminal ganglion infection by thymidine kinase-negative mutants of herpes simplex virus.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.