Linked Life Data

2243900

Source:http://linkedlifedata.com/resource/pubmed/id/2243900

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-1-3
pubmed:abstractText
The application of psychometric procedures to a normal population sample to detect individuals with increased liability for schizophrenia is a useful methodological adjunct to the traditional genetic high-risk strategy. A necessary and reasonable step in the process of establishing the utility of a viable psychometric index of schizotypy is the formal investigation of the latent structure of psychometric values. The present study used admixture analysis to examine the distribution of scores on the Perceptual Aberration Scale (PAS), an objective measure of hypothetical psychosis-proneness, in a randomly ascertained sample of 18-year-old university students (n = 707). We applied parametric methods that assumed normally distributed component distributions; viewed in this context, our results are hypothesis-generating and not definitive confirmation of specific hypotheses. Within our methodological framework, the results provide strong evidence for the commingling of normal distributions, even after allowing for unequal variances across components and after removing skewness. The overall distribution of power-transformed data is consistent with the existence of three qualitatively distinct classes of PAS responders. We discuss our results in light of Meehl's model of schizotaxia, a "mixed model" of inheritance of liability to schizophrenia, and we review the methodological implications of our findings for future research.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0165-1781
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-57
pubmed:dateRevised
2008-4-17
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Discerning the latent structure of hypothetical psychosis proneness through admixture analysis.
pubmed:affiliation
Department of Human Development, Cornell University, Ithaca, NY 14853-4401.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't