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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1991-1-3
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pubmed:abstractText |
An angiotensin II sensitivity test and a supine pressor test were done consecutively at 28 weeks gestation in 90 healthy, normotensive nulliparous women. None of the supine pressor tests was positive, applying the predefined threshold of a rise of 20 mmHg in diastolic blood pressure after rolling over; nine tests were positive using a corrected 9 mmHg cut-off level. Ten women had a positive angiotensin sensitivity test using a threshold of the effective pressor dose of 8 ng/kg/min; 22 women were positive using an effective pressor dose of less than or equal to 10 ng/kg/min. Later in pregnancy 12 women (13%) developed pregnancy-induced hypertensive disease (PIH). The specificity of both tests of predicting the development of PIH was about 90%. The sensitivity of the angiotensin sensitivity test at the 10 ng/kg/min level was 92%. Because of its low sensitivity of 25% the supine pressor test appears to have no value for the prediction of PIH. There was a significant positive association between angiotensin II refractoriness and birthweight.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
0306-5456
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
97
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
817-21
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2242367-Adult,
pubmed-meshheading:2242367-Angiotensin II,
pubmed-meshheading:2242367-Birth Weight,
pubmed-meshheading:2242367-Blood Pressure,
pubmed-meshheading:2242367-Female,
pubmed-meshheading:2242367-Humans,
pubmed-meshheading:2242367-Hypertension,
pubmed-meshheading:2242367-Infant, Newborn,
pubmed-meshheading:2242367-Pregnancy,
pubmed-meshheading:2242367-Pregnancy Complications, Cardiovascular,
pubmed-meshheading:2242367-Prospective Studies,
pubmed-meshheading:2242367-Sensitivity and Specificity,
pubmed-meshheading:2242367-Supination
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pubmed:year |
1990
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pubmed:articleTitle |
Prediction of pregnancy-induced hypertensive disorders by angiotensin II sensitivity and supine pressor test.
|
pubmed:affiliation |
Department of Obstetrics and Gynaecology, Erasmus University Medical School, Rotterdam, The Netherlands.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|