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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1990-12-12
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pubmed:abstractText |
We examined a 57-year-old woman who had bilateral corneal crystalline deposits associated with xanthelasma. The patient's son had bilateral stromal haze. Plasma cholesterol and apolipoprotein A-I and B levels were normal. Histopathologic examination disclosed lipid deposits, particularly in the superficial stroma and Bowman's layer. These deposits stained with oil red O and filipin, a fluorescent probe that specifically detects unesterified cholesterol. Cryoultramicrotomy disclosed more specific ultrastructural localization of unesterified cholesterol with an array of crystals resembling multiple plates in extracellular corneal tissue.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0002-9394
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
110
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
513-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2240137-Cataract,
pubmed-meshheading:2240137-Cataract Extraction,
pubmed-meshheading:2240137-Cholesterol,
pubmed-meshheading:2240137-Cornea,
pubmed-meshheading:2240137-Corneal Dystrophies, Hereditary,
pubmed-meshheading:2240137-Female,
pubmed-meshheading:2240137-Filipin,
pubmed-meshheading:2240137-Humans,
pubmed-meshheading:2240137-Keratoplasty, Penetrating,
pubmed-meshheading:2240137-Lenses, Intraocular,
pubmed-meshheading:2240137-Middle Aged
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pubmed:year |
1990
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pubmed:articleTitle |
Cholesterol localization in ultrathin frozen sections in Schnyder's corneal crystalline dystrophy.
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pubmed:affiliation |
Department of Ophthalmology, University of Maryland, Baltimore 21201.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|