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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1979-10-24
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pubmed:abstractText |
An influence of thyrotropin (TSH), dibutyryl cyclic AMP (dbcAMP), triiodothyronine (T3) and thyroxine (T4) on the mitotic incidence in the organ-cultured rat thyroid was studied. The study has revealed biphasic inhibitory and stimulatory effects of TSH on the thyroid mitotic activity. The inhibitory effect occurred 14 h after an exposure of the thyroid explants to TSH and was enhanced by T3. A similar inhibitory effect was observed after an exposure of the explants to dbcAMP. 24 h after the exposure of the thyroid explants to TSH a stimulatory effect on the mitotic incidence was observed. The latter effect was not reproduced by dbcAMP.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0013-7251
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
186-90
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:223838-Animals,
pubmed-meshheading:223838-Bucladesine,
pubmed-meshheading:223838-Male,
pubmed-meshheading:223838-Mitosis,
pubmed-meshheading:223838-Organ Culture Techniques,
pubmed-meshheading:223838-Rats,
pubmed-meshheading:223838-Thyroid Gland,
pubmed-meshheading:223838-Thyrotropin-Releasing Hormone,
pubmed-meshheading:223838-Thyroxine,
pubmed-meshheading:223838-Triiodothyronine
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pubmed:year |
1979
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pubmed:articleTitle |
Biphasic inhibitory and stimulatory effects of thyrotropin on the mitotic activity of thyroid explants cultured in vitro.
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pubmed:publicationType |
Journal Article
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