Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-12-21
pubmed:abstractText
Two encapsulated medullary carcinomas of the thyroid gland exhibiting an organoid and trabecular pattern with hyalinized stroma and composed of polyhedral to spindled tumor cells with hyaline-appearing cytoplasm are described and compared with three histologically indistinguishable adenomas of follicular cell derivation. Positive immunocytochemical staining for calcitonin and negative staining for thyroglobulin confirms the diagnosis of medullary carcinoma in these tumors, while positive staining for thyroglobulin confirms the follicular cell nature of the adenomas. The distinction between these tumor types is a crucial one, given the prognostic and potential genetic implications of medullary carcinoma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0893-3952
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
581-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Medullary carcinoma of the thyroid gland: an encapsulated variant resembling the hyalinizing trabecular (paraganglioma-like) adenoma of thyroid.
pubmed:affiliation
Department of Pathology and Laboratory Medicine, Mt. Sinai medical Center, Cleveland Ohio.
pubmed:publicationType
Journal Article, Comparative Study