Linked Life Data

2234776

Source:http://linkedlifedata.com/resource/pubmed/id/2234776

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1990-12-18
pubmed:abstractText
Attempts to treat patients suffering from metastasizing or primary operable breast cancer in a risk adapted fashion have always been dependent on the detection and clinically relevant ranking of prognostic parameters. Despite a variety of assumed prognostic parameters and description of prognostic indices no generally accepted definition of low or high risk breast cancer has been established as yet. Nevertheless, attempts have been successful to accomplish risk adapted treatment strategies that resulted in a substantial reduction in treatment related morbidity. Thus, replacement of surgical ablation procedures by drugs manipulating hormonal feedback regulation has yielded less side effects. Furthermore, new antiestrogens and antigestagens are aiming at a reduction in the rate and degree of toxicity. In addition, chemotherapy of metastasizing disease as well as adjuvant systemic therapy is being investigated with consideration of the concept of a maximum in efficacy and a minimum in toxicity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0378-584X
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
237-43
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Therapeutic aspects of low-risk breast cancer.
pubmed:affiliation
Innere Universitätsklinik und Poliklinik (Tumorforschung) Westdeutsches Tumorzentrum, Essen, FRG.
pubmed:publicationType
Journal Article, Review