Linked Life Data

223409

Source:http://linkedlifedata.com/resource/pubmed/id/223409

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1979-9-25
pubmed:abstractText
hCG-induced loss of hCG (LH) receptors and desensitization of adenylate cyclase in the pseudopregnant rat ovary have been studied. At various time intervals after hCG treatment, the decrease in hCG-stimulated adenylate cyclase activity was closely related to the reduction in available hCG receptors. The hCG-induced desensitization of adenylate cyclase and a fall in hCG binding activity were also dose-dependent and directly correlated. There were no changes in the affinity of receptors binding and in the apparent Km for adenylate cyclase activation. These findings indicate that the loss of hCG receptors is associated with desensitization of adenylate cyclase following the hCG injection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0065-2598
pubmed:author
pubmed:issnType
Print
pubmed:volume
112
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
717-22
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
hCG-induced loss of LH-hCG receptor and desensitization of adenylate cyclase.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.