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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
1990-12-5
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pubmed:abstractText |
Two platelet-derived growth factor A-chain proteins, termed short and long A chains, are generated as a result of alternative mRNA splicing of exon 6 of the A-chain gene. S1 nuclease mapping and polymerase chain reaction analyses demonstrate that both short and long A-chain transcripts are expressed in a variety of normal tissues. In addition, immunohistochemical localization of long A-chain protein reveals a cellular distribution identical to that observed with platelet-derived growth factor heteroserum.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2315311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2460450,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2479986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2479987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2543106,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2747650,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2779559,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2780289,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2832065,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2832727,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-2992937,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-3013421,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-3175624,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-3413486,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-3462731,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-3614364,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-6526008,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-6950377,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-7068680,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-7263691,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-7305965,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2233732-939761
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0270-7306
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6051-4
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2233732-Amino Acid Sequence,
pubmed-meshheading:2233732-Animals,
pubmed-meshheading:2233732-Base Sequence,
pubmed-meshheading:2233732-Exons,
pubmed-meshheading:2233732-Macromolecular Substances,
pubmed-meshheading:2233732-Male,
pubmed-meshheading:2233732-Mice,
pubmed-meshheading:2233732-Molecular Sequence Data,
pubmed-meshheading:2233732-Neoplasms, Experimental,
pubmed-meshheading:2233732-Oligonucleotide Probes,
pubmed-meshheading:2233732-Organ Specificity,
pubmed-meshheading:2233732-Platelet-Derived Growth Factor,
pubmed-meshheading:2233732-Polymerase Chain Reaction,
pubmed-meshheading:2233732-RNA, Messenger,
pubmed-meshheading:2233732-RNA Splicing,
pubmed-meshheading:2233732-Transcription, Genetic
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pubmed:year |
1990
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pubmed:articleTitle |
Alternatively spliced platelet-derived growth factor A-chain transcripts are not tumor specific but encode normal cellular proteins.
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pubmed:affiliation |
Division of Hematology-Oncology, Children's Hospital, Boston, Massachusetts.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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