Linked Life Data

2231663

Source:http://linkedlifedata.com/resource/pubmed/id/2231663

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1990-12-27
pubmed:abstractText
White blood cells have recently been implicated in the development of venous ulceration. Fifty subjects (14 normal controls, 21 with superficial venous insufficiency (SVI), and 15 with deep venous insufficiency (DVI] have been studied in the supine and dependent positions in a constant environment using video capillary microscopy, laser Doppler flowmetry and transcutaneous oxygen measurements to the gaiter skin. All three groups had an increase in visible capillary loops and a reduction in blood flux in the gaiter region when the leg was placed in the dependent position. There was a decrease in the leg/chest transcutaneous oxygen ratio in all three groups on dependency. These results suggest that the 'oedema protection reflex' (as measured by the laser Doppler probe) is present not only in normal and SVI limbs but also in DVI limbs. The increase in visible capillary loops suggests that intraluminal capillary occlusion is not occurring within the period of this study. The exact microvascular defecit of venous ulceration remains to be explained.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0309-1902
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
184-7
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
The microvascular lesion in venous ulceration and the role of the white blood cell.
pubmed:affiliation
Department of Surgical Studies, UCMSM, Middlesex Hospital, London, UK.
pubmed:publicationType
Journal Article