|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
1990-12-13
|
|
pubmed:abstractText |
We evaluated the recently described differential agglutination test (HS/AC test) to differentiate recently acquired toxoplasma infections from those acquired in the more distant past in sera obtained from 38 patients with carefully defined symptomatic and asymptomatic infections. AC antigens detect acute-phase-specific immunoglobulin G (IgG) antibodies against Toxoplasma gondii tachyzoites that are formed only during the acute stage of infection in humans. The HS/AC test correctly identified recently acquired infections in patients with toxoplasmic lymphadenopathy or asymptomatic infections (including infections in 7 women who seroconverted during gestation) in 31 of 33 patients. We also studied 15 individuals who had been infected for at least 2 years. In that group, only 13% had an acute pattern in the HS/AC test. However, the wide range in times from infection (from 2 to 14 years) did not allow for an estimate of when the pattern in the HS/AC test changed from acute to not acute. These results reveal that in the appropriate clinical situation, when both IgG and IgM tests are positive and a question still remains about the acuteness of infection, the HS/AC test may be useful for differentiating between toxoplasma infections acquired recently and those acquired in the more distant past.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-2681638,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-2778066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-2857860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-2926163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-3290240,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-3317730,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-3330458,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-3336419,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-342953,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-3517786,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-4580783,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-6885993,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-7000687,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-7000807,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2229374-7007520
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0095-1137
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
28
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1928-33
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:2229374-Agglutination Tests,
pubmed-meshheading:2229374-Animals,
pubmed-meshheading:2229374-Antibodies, Protozoan,
pubmed-meshheading:2229374-Evaluation Studies as Topic,
pubmed-meshheading:2229374-Female,
pubmed-meshheading:2229374-Humans,
pubmed-meshheading:2229374-Immunoglobulin G,
pubmed-meshheading:2229374-Immunoglobulin M,
pubmed-meshheading:2229374-Pregnancy,
pubmed-meshheading:2229374-Pregnancy Complications, Infectious,
pubmed-meshheading:2229374-Time Factors,
pubmed-meshheading:2229374-Toxoplasma,
pubmed-meshheading:2229374-Toxoplasmosis
|
|
pubmed:year |
1990
|
|
pubmed:articleTitle |
Differential agglutination test for diagnosis of recently acquired infection with Toxoplasma gondii.
|
|
pubmed:affiliation |
Department of Immunology and Infectious Diseases, Palo Alto Medical Foundation, California 94301.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
