Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1990-12-5
|
pubmed:abstractText |
Sixteen children with hGH deficiency were treated for a year with methionyl-somatotropin (Somatonorm) or recombinant-somatotropin (Genotropin). The hormone was administrated subcutaneously 3 time/week, 0.45-0.6 IU/kg/week. After a year of treatment, the mean growth rate in those who received Somatonorm increased from 3.96 +/- 0.8 cm/yr to 9.08 +/- 2.7 cm/yr, and in those who received Genotropin from 3.6 +/- 0.6 cm/yr to 8.58 +/- 1.1 cm/yr with no significant difference. No adverse effects were observed, but four children that received Somatonorm developed antihGH antibodies with a very low binding capacity, of less than 0.1 mg/L. All the children that received Genotropin were negative for antihGH antibodies.
|
pubmed:language |
spa
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0539-6115
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
47
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
369-71
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2222818-Adolescent,
pubmed-meshheading:2222818-Antibodies,
pubmed-meshheading:2222818-Child,
pubmed-meshheading:2222818-Child, Preschool,
pubmed-meshheading:2222818-Drug Administration Schedule,
pubmed-meshheading:2222818-Female,
pubmed-meshheading:2222818-Growth Disorders,
pubmed-meshheading:2222818-Growth Hormone,
pubmed-meshheading:2222818-Human Growth Hormone,
pubmed-meshheading:2222818-Humans,
pubmed-meshheading:2222818-Male,
pubmed-meshheading:2222818-Recombinant Proteins
|
pubmed:year |
1990
|
pubmed:articleTitle |
[Results of the treatment of growth hormone deficiency with methionine-somatotropin or recombinant somatotropin].
|
pubmed:affiliation |
Departamento de Endocrinología Hospital Infantil de México Federico Gómez, México.
|
pubmed:publicationType |
Journal Article,
English Abstract
|