Linked Life Data

2222331

Source:http://linkedlifedata.com/resource/pubmed/id/2222331

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1990-10-31
pubmed:abstractText
Cochleograms of guinea pig ears were made 30-40 days after exposure to intense pure tones of 300 Hz, 500 Hz, 2 kHz, or 4 kHz at 130-150 dB SPL for 4-24 h. At 4 kHz, hair cells in the basal turn disappeared totally, in the second turn moderately, and were relatively undamaged in the third and apical turns. At 500 Hz, hair cells in the second and third turns were almost completely injured and at 300 Hz moderately damaged in the third and apical turns although the basal turn remained undamaged. At 2 kHz for 9 h, hair cells were almost completely injured in all turns. Negative endocochlear DC potential (negative EP) induced by furosemide was observed in the basal turn but not in the third turn of animals exposed to 300 Hz. Contrarily, negative EP was observed in the third turn but not in the basal turn of animals exposed to 4 kHz. We conclude that the hair cells of Corti's organ play an essential role in the production of negative EP.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0385-8146
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
61-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Long-term effects of intense sound on hair cells of Corti's organ and endocochlear DC potential.
pubmed:affiliation
Department of Otorhinolaryngology, Miyazaki Medical College, Japan.
pubmed:publicationType
Journal Article