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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1990-11-19
|
| pubmed:abstractText |
Seroprevalence of human T-lymphotropic virus type 1 (HTLV-I) among a sample of persons selected from a government register of businesses in Trinidad was 3.2% in 1,025 persons of African descent compared to 0.2% among 487 persons of Asian descent and 0% among 46 persons of European-descent. In Tobago, from a coastal village, among persons of African ancestry ascertained as part of a cardiovascular survey, the rate was 11.4%, which was significantly higher when corrected for age and race than the rate in Trinidad. The seroprevalence rate of antibodies to hepatitis A and B was also significantly elevated in Tobago compared to Trinidad. HTLV-I seroprevalence rates were higher in females than males while hepatitis A and B rates were not significantly different in the two sexes. For males, age was a significant determinant of HTLV-I seropositivity, while for females, age, markers of poor sanitation, and hepatitis B were each independently linked to HTLV-I seropositivity. The frequent occurrence of multiple infectious exposures in persons of lower socioeconomic circumstances in this tropical environment may result in immune activation that heightens susceptibility to HTLV-I infection.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0894-9255
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
3
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1102-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2213511-Adult,
pubmed-meshheading:2213511-Africa,
pubmed-meshheading:2213511-Chi-Square Distribution,
pubmed-meshheading:2213511-Cohort Studies,
pubmed-meshheading:2213511-Female,
pubmed-meshheading:2213511-Follow-Up Studies,
pubmed-meshheading:2213511-HTLV-I Antibodies,
pubmed-meshheading:2213511-HTLV-I Infections,
pubmed-meshheading:2213511-Hepatitis A,
pubmed-meshheading:2213511-Hepatitis B,
pubmed-meshheading:2213511-Hepatitis B Antibodies,
pubmed-meshheading:2213511-Humans,
pubmed-meshheading:2213511-Male,
pubmed-meshheading:2213511-Prevalence,
pubmed-meshheading:2213511-Regression Analysis,
pubmed-meshheading:2213511-Risk Factors,
pubmed-meshheading:2213511-Serologic Tests,
pubmed-meshheading:2213511-Social Class,
pubmed-meshheading:2213511-Social Environment,
pubmed-meshheading:2213511-Trinidad and Tobago
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
A study of HTLV-I and its associated risk factors in Trinidad and Tobago.
|
| pubmed:affiliation |
Viral Epidemiology Section, National Cancer Institute, Bethesda, Maryland 20892.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|